Value of Measuring Animal Body Temperatures in Research
Body temperature is a fundamental parameter for evaluating health status of an animal in the clinical or research setting. Temperature is also a valuable biomarker to determine humane end points for animal welfare, as well as a useful clinical indicator for evaluating disease onset and progression in infectious disease models.
Although body temperature data is such a useful readout in research studies, it is often not evaluated due to measurement challenges. Rectal thermometry is the most common method used for core temperature measurements, but this technique is not only time- and labor-intensive, but also can lead to significant animal distress due to manual restraint required for device insertion. Non-contact infrared thermometry is less invasive, but this method can be influenced by external ambient temperatures, which can lead to inaccurate temperature readings. Therefore, a practical and reliable method for routine temperature measurements in research animals is required.
Reliable and Convenient Method for Monitoring Animal Body Temperature
The UID Temperature Monitoring System circumvents the challenges confronted with other temperature collection methods and provides a practical, reliable and non-intrusive means for frequent temperature measurements. It is designed for acquiring accurate temperature readings from conscious and unrestrained laboratory animals, reducing stress and ensuring reliable data.
The UID Temperature Monitoring System consists of a small microchip with an integrated temperature biosensor, an RFID reader that retrieves the temperature data with a quick and simple scan, and a specialized injection device for implanting the microchip.
Components of the UID Temperature Monitoring System
Temperature Microchip
A miniature RFID transponder with integrated temperature biosensor.
- Temperature accuracy: ±0.1°C @ 38°C
- Temperature resolution: ±0.1°C
- Temperature range: 25°C – 50°C
- Small Size: 2.1mm x 13mm
- Individually packaged in sterile cannula for quick and easy insertion
Reader
A range of microchip readers designed to meet your specific research need and workflow
- Stationary or mobile applications
- Battery or A/C powered
- Handheld or desktop
- Bluetooth/USB/HID communication
A selection of microchip injector systems are available to meet the specific application.
- Designed for error-free, quick and easy microchip injection
- Reusable
- Subcutaneous, intramuscular or intraperitoneal injection
Convenient and Easy to Use
Subcutaneous microchip implantation is quick and minimally invasive, requiring only injection of the microchip through a sterile hypodermic needle. After implantation, measuring the animal’s temperature is completely noninvasive and easily collected with a simple scan, and as often as needed.
Accurate Temperature Readings
The UID Temperature Microchip is the only GLP-validated, temperature transponder available for laboratory animal research with unmatched accuracy to ±0.1o C @ 38oC. Reliable temperature measurements are reported in 0.1o C increments within the 25oC – 50oC temperature range.
Simple Temperature Measurements
Routine temperature measurements are obtained non-intrusively with a quick and simple scan from a compatible reader. The reader is waived within a few centimeters from the implantation site until the temperature transponder is detected, then the animal’s temperature and identification code are displayed on the screen.
More Research Data
In addition to providing temperature and unique ID, each temperature-sensing microchip contains up to 16 alphanumeric characters of on-board memory for programming with any customized coding sequence, which might be used to represent information such as the study number, genotype, investigator name, project number, animal’s sex, or animal’s date of birth.
Automatic Data Collection
UID readers connect easily to a computer via wireless or serial link communication. This feature allows for automatic import of temperature and animal ID directly into an Excel spreadsheet or Laboratory Information Management System (LIMS).
Benefits
Why Choose UID Over Competitors?
Superior Quality & Reliability
- UID offers the only GLP-validated, temperature microchip on the market.
- Durable, high-quality readers with low repair rate.
- UID microchips are manufactured under stringent quality standards which result in extremely low failure rates (1 PPM), compared to the 1-5% failure rates reported by users of competitor microchips.
Unmatched Accuracy
- The UID temperature microchip is the only GLP-validated, temperature transponder available for laboratory research with unsurpassed accuracy of ±0.1o C @ 38o C, compared to the 0.2-0.5o C accuracy reported by other vendors of temperature microchips.
Greater Flexibility & Versatility
- UID universal readers are designed to read any UID microchip, compared to the competitor, which offers dedicated readers for each microchip type.
- UID offers a wide range of readers available with multiple read distances to meet the specific process and application.
Improved Features
- Maintain sterility: UID microchips are available in sterile cannula and packaged individually in blister pack, compared to competitor microchips, which are provided as multiple injectors in a tray, which compromises sterility once opened.
- Smaller size: The UID Temperature microchip is smaller (2.1mm x 13mm) in size compared to the competitor microchip (2.2mm x 14mm)
- Eco-friendly: UID microchips are provided in disposable cannula for use with a reusable injector, compared to our competitor which offers disposable, plastic applicators for each microchip.
- UID readers are FCC compliant.
- UID readers can be set to continuous mode for frequent and continuous temperature data collection (as often as every 1-5 seconds).
Lower Costs
- Lower cost readers and microchips compared to competitor prices.
- All UID microchips can be used with any of our universal scanners, compared to our competitor which offers a dedicated scanner for each microchip type.
Exceptional Customer Service and Support
- We provide IT-integration support to ensure seamless data transfer.
- We deliver dedicated customer support for product installation and training.
- We offer a 30-day, risk-free equipment trial.
- We are scientists, and we understand our client’s needs.
- We care! Customer satisfaction is our top priority.
All Species
Research Applications
Home Cage Temperature & Activity Monitoring
- Continuous, real time (24/7) recording of animal location, movement and temperature.
- Undisturbed, remote monitoring of Group Housed animal activity.
- Individual monitoring of up to 5 mice per cage.
- Objective monitoring of animal behavior at night when the lights are off and rodents are most active.
- Create your own Smart Cage for rodent activity monitoring.
A Method to Facilitate COVID-19 Research
The UID Temperature Monitoring System is ideal for COVID-19 studies designed for evaluating the safety and efficacy of emerging therapeutics and vaccines in animal models. Increased interest is coming within Contract Research Organizations (CROs) that supply animal models and services to the pharmaceutical industry. Taconic Biosciences, a global leader in drug discovery animal models and services, has integrated RFID temperature monitoring technology into its portfolio, catering to COVID-19 and other disease models. Taconic Biosciences provides clients animal models equipped with pre-embedded UID temperature biosensors, facilitating temperature data acquisition with a quick and simple UID reader scan. This service is designed to enhance COVID-19 research by streamlining routine temperature collection processes, thus saving time and accelerating research results.
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